PT-141 (Bremelanotide), a libido booster peptide

PT-141, scientifically known as bremelanotide, is a synthetic peptide and melanocortin receptor agonist under investigation for its potential to address sexual dysfunction. It uniquely influences sexual arousal through central nervous system pathways rather than focusing on vascular mechanisms, distinguishing it from other treatments such as PDE5 inhibitors. PT-141 has gained approval for the management of generalized hypoactive sexual desire disorder (HSDD) in premenopausal women, demonstrating its clinical relevance. Requires reconstitution before use.

What is PT-141?

• PT-141 (brand name: Bremelanotide) is a cyclic peptide that enhances sexual desire and response;
• Unlike other medications, PT-141 targets the central nervous system directly to increase libido and improve blood circulation to the genitals of both men and women.
• It stimulates the release of dopamine in your brain, the neurotransmitter that regulates libido and sexual motivation.

Why it's Amazing? 

• Boosted sex drive: PT-141 directly increase libido levels by stimulating dopamine release, which enhances sexual motivation;
• Backed by science: Several clinical studies have shown PT-141 to induce erectile response in men and improve levels of sexual desire in women;
• Non-invasive administration: A nasal spray formulation can deliver PT-141 more absorption into brain with less degradation and no pain of injection.

Chemical information:

• Cat. #: QT-2105
• CAS#189691-06-3
• Formula: C₅₀H₆₈N₁₄O₁₀
• Sequence: Ac-Nle-Asp(1)-His-D-Phe-Arg-Trp-Lys(1)-OH
• M.W.: 1025.2 g/mol

Chemical Structure: