Acetyl Tetrapeptide-5 (Eyeseryl®)

Acetyl Tetrapeptide-5 (Eyeseryl®)

Acetyl Tetrapeptide-5, commonly known by its trademark Eyeseryl®, is a clinically backed cosmetic peptide solution designed to visibly reduce under-eye puffiness, eye bags, and dark circles. Sourced from naturally derived amino acids, this tetrapeptide improves lymphatic circulation, reduces water retention, and increases skin elasticity for a refreshed and youthful eye contour.

Acetyl Tetrapeptide-5 (Eyeseryl) Benefits

• Reduces the appearance of under-eye bags and puffiness
• Improves skin elasticity in the delicate periorbital region
• Visibly decreases the appearance of dark circles
• Strengthens skin for long-lasting firming and protective effects
• Suitable for sensitive skin and daily eye care use

Mechanism of Action

Eyeseryl® peptide targets the physiological causes of puffiness:

• Enhances lymphatic drainage to reduce fluid buildup
• Minimizes capillary permeability, decreasing localized swelling
• Helps restore firmness and smoothness in the under-eye skin

These actions make it an ideal ingredient in anti-fatigue and anti-aging eye formulations.

Clinical & In Vivo Results

• 70% reduction in puffiness within 28 days
• Noticeable improvement in as few as 14 days
• 30% increase in skin elasticity in just 30 days
• Reduction in dark circle visibility in a majority of test subjects

Eyeseryl vs Dipeptide-2 Differences

• Eyeseryl® targets water retention and elasticity, acting on lymphatic drainage and vascular permeability.
• Dipeptide-2 primarily supports lymphatic circulation and ACE inhibition, more focused on edema.

These peptides can be complementary, but Eyeseryl® stands out for multifunctional eye area rejuvenation.

Eyeseryl Peptide Anti-Puffiness Use

Eyeseryl peptide is widely recognized for its anti-puffiness use in advanced skincare formulations targeting the delicate eye area. By enhancing lymphatic drainage and reducing capillary permeability, Eyeseryl effectively diminishes swelling and fluid retention under the eyes, making it a key ingredient in serums and creams designed to combat puffiness and refresh tired-looking eyes.

Specifications

• INCI Name: Acetyl Tetrapeptide-5
• Synonym: EYESERYL®
• Sequence: Ac-β-Ala-His-Ser-His-OH
• Molecular Formula: C₂₀H₂₈N₈O₇
• Molecular Weight: 492.5 g/mol
• CAS Number: 820959-17-9
• FDA UNII: D1HW9N9QBX
• Functions: Anti-puffiness | Anti-dark circles | Firming | Protective

Where to Buy Eyeseryl Peptide

Looking for a reliable source of Eyeseryl® peptide for under-eye bags or to include in your eye cream or serum formulations? Buy Eyeseryl® peptide anti-puffiness use online now from our trusted marketplace for cosmetic-grade peptides and active ingredients.