{"product_id":"α-endorphin","title":"α-Endorphin","description":"\u003ch2\u003eOverview\u003c\/h2\u003e\n\u003cp\u003eα-Endorphin (also known as alpha-endorphin or LPH(61-76)) is an endogenous opioid peptide naturally produced in the pituitary gland and central nervous system. This 16-amino acid peptide plays a significant role in pain modulation, stress response, and emotional regulation.\u003c\/p\u003e\n\u003ch2\u003eMolecular Properties\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS Number:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e59004-96-5\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e1745.95\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eC₇₇H₁₂₀N₁₈O₂₆S\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e≥97%\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eMechanism of Action\u003c\/h2\u003e\n\u003cp\u003eα-Endorphin exerts its effects by binding to mu, delta, and kappa opioid receptors throughout the nervous system. This binding activates inhibitory G-proteins, leading to a cascade of events:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eReduced cAMP levels:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eDecreased levels of cyclic adenosine monophosphate.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCalcium channel closure:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eReduced influx of calcium ions into neurons.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePotassium channel opening:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eIncreased efflux of potassium ions from neurons.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThese changes result in decreased neurotransmitter release, ultimately modulating pain perception and emotional responses.\u003c\/p\u003e\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\n\u003cp\u003eα-Endorphin is a valuable tool in neuroscience research, allowing scientists to study:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eEndogenous opioid system:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eThe body's natural pain management and stress response mechanisms.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePain pathways:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eUnderstanding the neurochemical processes underlying pain perception.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStress response:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eInvestigating the role of opioids in coping with stress.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReward systems:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eExploring the involvement of opioids in reward and motivation.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eResearch with α-endorphin contributes significantly to advancements in neurobiology and endocrinology, enhancing our understanding of the body's natural homeostasis and stress management capabilities.\u003c\/p\u003e\n\u003ch2\u003eConclusion\u003c\/h2\u003e\n\u003cp\u003eα-Endorphin's role as an endogenous opioid peptide is crucial to the body's natural pain management and stress response systems. Further research using α-endorphin continues to unlock valuable insights into these complex biological processes.\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e\u003cmeta charset=\"UTF-8\"\u003e\u003c\/p\u003e","brand":"QUALITIDE","offers":[{"title":"10 MG","offer_id":50103642915062,"sku":"QT-2005-10MG","price":99.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0797\/4849\/7654\/files\/Endorphin-10mg.png?v=1773334058","url":"https:\/\/triskly.com\/products\/%ce%b1-endorphin","provider":"Triskly","version":"1.0","type":"link"}